Irish Multiple Myeloma Society’s Inaugural Meeting

The Irish Multiple Myeloma Society’s (IMMS) Inaugural Meeting took place on Friday, September 12th 2025, in The Gibson Hotel, Dublin, bringing together clinicians, researchers and healthcare professionals from across Ireland and abroad for a full day of talks and discussions on current and emerging developments in Multiple Myeloma.

Professor Paul Browne opened the meeting by welcoming attendees and introducing the IMMS.

The first session opened with Chairs, Professor John Quinn and Professor Siobhán Glavey, addressing “Multiple Myeloma advances in Upfront and Relapsed Disease”.

Professor Philippe Moreau (Nantes University Hospital) joined virtually and discussed “Frontline Therapy of Transplant – Eligible Patients”.

Dr Alessandra Larocca (University Hospital Città della Salute e della Scienza, Torino) discussed “How I Treat Frail Myeloma Patients”.

Dr Rakesh Popat (UCH, London) outlined “Novel Immunotherapies for Relapsed Multiple Myeloma: working out how to use them”, followed by Dr Tony McElligott, The John Durkan Leukaemia Laboratory, (TTMI) who spoke about “Modelling Myeloma: Preclinical Drug Development”.

The second session of the day began with Chairs Dr Mark Coyne, Dr Irene Ghobrial and Dr Patrick Hayden, exploring “Cellular and Immune Therapies current practice horizons”.

Professor Michael O’Dwyer (University of Galway) then discussed “Glycosylation based immune evasion in Multiple Myeloma: rationale for sialidase armoured CAR-NK cells”.

Dr Catherine Duane (Beaumont Hospital, Dublin) talked about “Extramedullary Disease in the Era of Cellular and Immunotherapies”, following by Paul Dowling (Maynooth University) on “Leveraging Proteomics for Precision Blood Cancer Research – Understanding the Challenges and Opportunities that exist”, and a virtual talk from Dr Eric Smith (Dana-Farber Cancer Institute) on “From bench to bedside: Emerging Horizons in Immune and Cell-Based Therapies for Myeloma – Dual Targeting and Delivery”.

The final session started with Chairs Professor Paul Browne, Dr Rakesh Popat and Professor Peter O’Gorman and it turned to “Smouldering Myeloma”. Professor Kwee Yong (UCH, London) discussed “Smouldering myeloma: Immune surveillance and evasion as a basis for interception strategies?” and Dr Irene Ghobrial (Dana-Farber Cancer Institute) presented “Risk Stratification of Smouldering Myeloma”.

Throughout the day, there were opportunities for discussion and exchange, as well as viewing the poster displays. The meeting concluded with the presentation of poster awards, recognising the work of early-career researchers.

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